LymphedemaV1, Main, Exploration, bibRecord, 006191

Lymphatics in Human Lymphatic Filariasis: In Vitro Models of Parasite-Induced Lymphatic Remodeling

Identifieur interne : 006191 ( Main/Exploration ); précédent : 006190; suivant : 006192

Lymphatics in Human Lymphatic Filariasis: In Vitro Models of Parasite-Induced Lymphatic Remodeling

Auteurs : Sasisekhar Bennuru ; Thomas B. Nutman

Source :

Lymphatic Research and Biology [ 1539-6851 ] ; 2009.

RBID : PMC:2883472

Descripteurs français

KwdFr :
- Animaux, Filariose lymphatique (anatomopathologie), Filariose lymphatique (immunologie), Filariose lymphatique (parasitologie), Humains, Modèles animaux de maladie humaine, Système lymphatique (physiologie), Techniques in vitro.
MESH :
- anatomopathologie : Filariose lymphatique.
- immunologie : Filariose lymphatique.
- parasitologie : Filariose lymphatique.
- physiologie : Système lymphatique.
- Animaux, Humains, Modèles animaux de maladie humaine, Techniques in vitro.

English descriptors

KwdEn :
- Animals, Disease Models, Animal, Elephantiasis, Filarial (immunology), Elephantiasis, Filarial (parasitology), Elephantiasis, Filarial (pathology), Humans, In Vitro Techniques, Lymphatic System (physiology).
MESH :
- immunology : Elephantiasis, Filarial.
- parasitology : Elephantiasis, Filarial.
- pathology : Elephantiasis, Filarial.
- physiology : Lymphatic System.
- Animals, Disease Models, Animal, Humans, In Vitro Techniques.

Abstract

Lymphatic filariasis characterized by the dysfunction of the lymphatics can lead to severe (and often) irreversible lymphedema and elephantiasis. Decades of research in the field shows that the establishment of the adult parasites in the lymphatics triggers a cascade of events that ultimately results in tissue scarring and fibrosis. In this minireview, we focus on the studies addressing the mechanisms underlying the parasite-induced lymphatic dilatation that suggests parasite-induced lymphatic remodeling and lymphangiogenesis may be the prelude towards developing chronic and irreversible filarial pathology.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883472

DOI: 10.1089/lrb.2009.0022
PubMed: 20143920
PubMed Central: 2883472

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Lymphatics in Human Lymphatic Filariasis: <italic>In Vitro</italic>
 Models of Parasite-Induced Lymphatic Remodeling</title>
<author><name sortKey="Bennuru, Sasisekhar" sort="Bennuru, Sasisekhar" uniqKey="Bennuru S" first="Sasisekhar" last="Bennuru">Sasisekhar Bennuru</name>
</author>
<author><name sortKey="Nutman, Thomas B" sort="Nutman, Thomas B" uniqKey="Nutman T" first="Thomas B." last="Nutman">Thomas B. Nutman</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">20143920</idno>
<idno type="pmc">2883472</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883472</idno>
<idno type="RBID">PMC:2883472</idno>
<idno type="doi">10.1089/lrb.2009.0022</idno>
<date when="2009">2009</date>
<idno type="wicri:Area/Pmc/Corpus">003057</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003057</idno>
<idno type="wicri:Area/Pmc/Curation">003056</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003056</idno>
<idno type="wicri:Area/Pmc/Checkpoint">003677</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">003677</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">002B68</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002B68</idno>
<idno type="wicri:Area/PubMed/Curation">002B68</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002B68</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002B68</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002B68</idno>
<idno type="wicri:Area/Ncbi/Merge">003914</idno>
<idno type="wicri:Area/Ncbi/Curation">003914</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">003914</idno>
<idno type="wicri:doubleKey">1539-6851:2009:Bennuru S:lymphatics:in:human</idno>
<idno type="wicri:Area/Main/Merge">006266</idno>
<idno type="wicri:Area/Main/Curation">006191</idno>
<idno type="wicri:Area/Main/Exploration">006191</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Lymphatics in Human Lymphatic Filariasis: <italic>In Vitro</italic>
 Models of Parasite-Induced Lymphatic Remodeling</title>
<author><name sortKey="Bennuru, Sasisekhar" sort="Bennuru, Sasisekhar" uniqKey="Bennuru S" first="Sasisekhar" last="Bennuru">Sasisekhar Bennuru</name>
</author>
<author><name sortKey="Nutman, Thomas B" sort="Nutman, Thomas B" uniqKey="Nutman T" first="Thomas B." last="Nutman">Thomas B. Nutman</name>
</author>
</analytic>
<series><title level="j">Lymphatic Research and Biology</title>
<idno type="ISSN">1539-6851</idno>
<idno type="eISSN">1557-8585</idno>
<imprint><date when="2009">2009</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Disease Models, Animal</term>
<term>Elephantiasis, Filarial (immunology)</term>
<term>Elephantiasis, Filarial (parasitology)</term>
<term>Elephantiasis, Filarial (pathology)</term>
<term>Humans</term>
<term>In Vitro Techniques</term>
<term>Lymphatic System (physiology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Filariose lymphatique (anatomopathologie)</term>
<term>Filariose lymphatique (immunologie)</term>
<term>Filariose lymphatique (parasitologie)</term>
<term>Humains</term>
<term>Modèles animaux de maladie humaine</term>
<term>Système lymphatique (physiologie)</term>
<term>Techniques in vitro</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Filariose lymphatique</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Filariose lymphatique</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Elephantiasis, Filarial</term>
</keywords>
<keywords scheme="MESH" qualifier="parasitologie" xml:lang="fr"><term>Filariose lymphatique</term>
</keywords>
<keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Elephantiasis, Filarial</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Elephantiasis, Filarial</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Système lymphatique</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Lymphatic System</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Disease Models, Animal</term>
<term>Humans</term>
<term>In Vitro Techniques</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Humains</term>
<term>Modèles animaux de maladie humaine</term>
<term>Techniques in vitro</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><title>Abstract</title>
<p>Lymphatic filariasis characterized by the dysfunction of the lymphatics can lead to severe (and often) irreversible lymphedema and elephantiasis. Decades of research in the field shows that the establishment of the adult parasites in the lymphatics triggers a cascade of events that ultimately results in tissue scarring and fibrosis. In this minireview, we focus on the studies addressing the mechanisms underlying the parasite-induced lymphatic dilatation that suggests parasite-induced lymphatic remodeling and lymphangiogenesis may be the prelude towards developing chronic and irreversible filarial pathology.</p>
</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Bennuru, Sasisekhar" sort="Bennuru, Sasisekhar" uniqKey="Bennuru S" first="Sasisekhar" last="Bennuru">Sasisekhar Bennuru</name>
<name sortKey="Nutman, Thomas B" sort="Nutman, Thomas B" uniqKey="Nutman T" first="Thomas B." last="Nutman">Thomas B. Nutman</name>
</noCountry>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 006191 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 006191 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:2883472
   |texte=   Lymphatics in Human Lymphatic Filariasis: In Vitro Models of Parasite-Induced Lymphatic Remodeling
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:20143920" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a LymphedemaV1

This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024

Serveur d'exploration sur le lymphœdème

Lymphatics in Human Lymphatic Filariasis: In Vitro Models of Parasite-Induced Lymphatic Remodeling

Lymphatics in Human Lymphatic Filariasis: In Vitro Models of Parasite-Induced Lymphatic Remodeling

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.